The story follows Joe (Cage), a down-on-his-luck truck driver haunted by the memory of his deceased wife and child. He meets Julie (Potente), a spiritually gifted woman who enlists Joe in a desperate effort to find the lost soul of her comatose daughter, Billie (Mitchell). But the spirit of Joe's dead wife Mary proves stronger, possessing the young woman's body and determined to settle her unfinished business with the living.

Diane Walters, an over-burdened mother of two with a third child on the way, strives to create the perfect Christmas while her loving but dysfunctional family falls apart around her.